Hypokalemic Periodic Paralysis and Renal tubular Acidosis as Presenting Manifestation of Primary Sjogren’s Syndrome - A Case Report
Keywords:
Hypokalemic periodic paralysis, Sjogren’s syndrome, Quadriparesis
Abstract
Among wide list of differentials of periodic paralysis, hypokalemia is an important cause. However hypokalemia with respiratory failure as sole presenting feature of Sjogren’s syndrome (SS) is rarely reported. We report a case of recurrent hypokalemic paralysis which presented with life threatening respiratory failure in second episode, hypokalemia was found due to distal renal tubular acidosis and on further investigation diagnosis of primary SS was made. In this article we emphasize need for detailed work-up of a case of recurrent hypokalemic periodic paralysis in order to identify the underlying etiology and do timely management in order to avoid future recurrence.
References
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secondary to distal renal tubular acidosis. Rheumatol Int 2013;33:1879-82.
5. Khandelwal D, Bhattacharya S, Khadgawat R, Kaur S, Tandon N, Ammini AC. Hypokalemic paralysis as a presenting
manifestation of primary Sjögren’s syndrome : A0 report of two cases. Indian J Endocrinol Metab 2012;16:853-5.
6. M Goroshi, S Khare, T Jamale,NS Shah. Primary Sjogren’s syndrome presenting as hypokalemic paralysis: A case series:
J Postgrad Med. 2017;63(2):128–131.
7. FoxRI.Sjögren’ssyndrome. Lancet2005;366:321-31.
8. Maripuri S, Grande JP, Osborn TG, Fervenza FC, Matteson EL, Donadio JV, et al. Renal involvement in primary Sjögren’s
syndrome: A clinicopathologic study. Clin J Am Soc Nephrol 2009;4:1423-31.
9. Chen LH, Hsu PN, Chen MY, Lee KL, Hsieh SC, Yu CL. Renal tubular acidosis in patients with primary Sjogren’s
syndrome. JRheumatol2007;21:13–9.
10. Both T, Hoorn EJ, Zietse R, van Laar JA, Dalm VA, Brkic Z, et al. Prevalence of distal renal tubular acidosis in primary
Sjögren’s syndrome. Rheumatology (Oxford) 2015;54:933-9.
11. Fraer M. A mask and many faces: hypokalemic periodic paralysis. South Med J 2008;101:887.
12. Rao N, John M, Thomas N, Rajaratnam S, Seshadri MS. Aetiological, clinical and metabolic profile of hypokalaemic
periodic paralysis in adults:
patient with Sjogren’s syndrome and distal renal tubular acidosis. J Am Soc Nephrol. 1992;3:264–71.
2. Soy M, Pamuk ON, Gerenli M, Celik Y. A primary Sjogren’s syndrome patient with distal renal tubular acidosis, who
presented with symptoms of hypokalemic periodic paralysis. Rheumatol Int 2005;26:86 – 9.
3. Bossini N, Savoldi S, Franceschini F, Mombelloni S, Baronio M, Cavazzana I, et al. Clinical and morphological features of
kidney involvement in primary Sjögren’s syndrome. Nephrol Dial Transplant. 2001;16:2328–36.
4. Yilmaz H, Kaya M, Özbek M, ÜUreten K, Safa Yildirim I. Hypokalemic periodic paralysis in Sjogren’s syndrome
secondary to distal renal tubular acidosis. Rheumatol Int 2013;33:1879-82.
5. Khandelwal D, Bhattacharya S, Khadgawat R, Kaur S, Tandon N, Ammini AC. Hypokalemic paralysis as a presenting
manifestation of primary Sjögren’s syndrome : A0 report of two cases. Indian J Endocrinol Metab 2012;16:853-5.
6. M Goroshi, S Khare, T Jamale,NS Shah. Primary Sjogren’s syndrome presenting as hypokalemic paralysis: A case series:
J Postgrad Med. 2017;63(2):128–131.
7. FoxRI.Sjögren’ssyndrome. Lancet2005;366:321-31.
8. Maripuri S, Grande JP, Osborn TG, Fervenza FC, Matteson EL, Donadio JV, et al. Renal involvement in primary Sjögren’s
syndrome: A clinicopathologic study. Clin J Am Soc Nephrol 2009;4:1423-31.
9. Chen LH, Hsu PN, Chen MY, Lee KL, Hsieh SC, Yu CL. Renal tubular acidosis in patients with primary Sjogren’s
syndrome. JRheumatol2007;21:13–9.
10. Both T, Hoorn EJ, Zietse R, van Laar JA, Dalm VA, Brkic Z, et al. Prevalence of distal renal tubular acidosis in primary
Sjögren’s syndrome. Rheumatology (Oxford) 2015;54:933-9.
11. Fraer M. A mask and many faces: hypokalemic periodic paralysis. South Med J 2008;101:887.
12. Rao N, John M, Thomas N, Rajaratnam S, Seshadri MS. Aetiological, clinical and metabolic profile of hypokalaemic
periodic paralysis in adults:
Published
2020-07-07
How to Cite
Dr. Saurabh Gupta, Dr. Shikha Gupta , Dr. Naushad Ravjani. (2020). Hypokalemic Periodic Paralysis and Renal tubular Acidosis as Presenting Manifestation of Primary Sjogren’s Syndrome - A Case Report. The Indian Practitioner, 73(6), 47-49. Retrieved from http://articles.theindianpractitioner.com/index.php/tip/article/view/992
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Case Reports
