A Case of Carcinoma Stomach Presenting as Cardiac Tamponade
Abstract
Cardiac tamponade originating from a primary gastric cancer (GC) is a rare condition. Patients are generally asymptomatic until the disease is advanced, and therefore, early diagnosis is difficult. We report a case of a 43- ear-old male admitted with progressive dyspnea and diagnosed to have cardiac tamponade on two- imensional (2D) echocardiography.
Pericardial fluid cytological examination was suggestive of metastatic adenocarcinoma. He underwent abdominal computed tomography scan, which showed thickening of the gastric wall and several mesenteric lymph nodes. Endoscopic examination of the stomach disclosed malignant ulcer along the lesser curvature, and iopsy of gastric ulcer revealed signet ring cell adenocarcinoma. Our patient presented with cardiac tamponade as the first manifestation of primary GC.
References
2. A. Al-Mamgani, L. Baartman, M. Baaijens, I et al. Cardiac metastases. Int J Clin Oncol, 13 (2008), pp. 369-372.
3. A. Moriyama, I. Murata, T. Kuroda, et al. Pericardiac metastasis from advanced gastric cancer. J Gastroenterol, 30 (1995),
pp. 512-516.
4. Abrams HL, Spiro R, Goldstein N. Metastases in carcinoma; analysis of 1000 autopsied cases. Cancer. 1950; 3:74-85.
5. Mukai K, Shinkai T, Tominaga K, Shimosato Y. The incidence of secondary tumors of the heart and pericardium: a
10-year study. Jpn J Clin Oncol. 1988; 18:195-201.
6. Klatt EC, Heitz DR. Cardiac metastases. Cancer. 1990; 65:1456-1459.
7. Kobayashi M, Okabayashi T, Okamoto K, Namikawa T, Araki K. Clinicopathological study of cardiac tamponade
due to pericardial metastasis originating from gastric cancer. World J Gastroenterol. 2005; 11:6899–904.
8. Y. Baba, S. Ishikawa, K. Ikeda, et al. A patient with 43 synchronous early gastric carcinomas with a Krukenberg tumor
and pericardial metastasis. Gastric Cancer, 10 (2007), pp. 135- 139.
9. E. Otsuji, T. Yamaguchi, K. Sawai, T. Takahashi. Characterization of signet ring cell carcinoma of the stomach.
J Surg Oncol, 67 (1998), pp. 216-220
10. S. Di Cosimo, G. Ferretti, N. Fazio, et al. Breast and ovarian metastatic localization of signet-ring cell gastric carcinoma.
Ann Oncol, 14 (2003), pp. 803-804.