Splenomegaly - A Diagnostic Dilemma
Keywords:
Splenomegaly, Primary splenic lymphoma, Non-Hodgkin’s lymphoma
Abstract
Splenic marginal zone lymphoma is a rare form of malignant neoplasm, a subtype of Non-Hodgkin’s Lymphoma. It is usually present in middle age group with unexplained splenomegaly, abdominal pain, fatigue and weight loss. It is also known as Primary Splenic Lymphoma. Splenectomy is usually chosen as a mode for both diagnosis and treatment. Here we present a case of a 37 years old female with massive splenomegaly who was later diagnosed to have primary splenic lymphoma.
References
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2. Kraemer BB, Osborne BM, Butler JJ. Primary splenic presentation of malignant lymphoma and related disorders. A study of 49 cases. Cancer. 1984 Oct 15;54(8):1606-19.
3. Swerdlow S, Campo E, Harris N, Jaffe E, Pileri S, Stein H, Thiele J, Arber D, Hasserjian R, Le Beau M, Orazi A, Seibert R. WHO Classification Of Tumors of Hematopoietic and Lymphoid Tissues. 4th ed. 2017. p. 185-187.
4. Camacho FI, Mollejo M, Mateo MS, Algara P, Navas C, Hernández JM, Santoja C, Solé F, Sánchez-Beato M, Piris MA. Progression to large B-cell lymphoma in splenic marginal
zone lymphoma: a description of a series of 12 cases. The American Journal of Surgical Pathology. 2001 Oct 1;25(10):1268-76.
5. Gao X, Li J, Lin J, Liu D, Yu L, Wang Q. High-grade transformation in a splenic marginal zone lymphoma with a cerebral manifestation. The American Journal of Case Reports.
2017;18:611.
6. Dufresne SD, Felgar RE, Sargent RL, Surti U, Gollin SM, McPhail ED, Cook JR, Swerdlow SH. Defining the borders of splenic marginal zone lymphoma: a multiparameter study. Human Pathology. 2010 Apr 1;41(4):540-51.
Published
2020-10-27
How to Cite
Dr. Aarohi Doshi , Dr. Rishi Patel , Dr. Purwa Doke. (2020). Splenomegaly - A Diagnostic Dilemma. The Indian Practitioner, 73(10), 29-32. Retrieved from https://articles.theindianpractitioner.com/index.php/tip/article/view/1067
Section
Case Reports
