Clinical Profile of Covid-19 Infected Patients Admitted in a Tertiary Care Hospital in Western India

Dr. Virendra Pratap Singh, Dr. Arundhati Diwan, Dr. Supriya Barsode, Dr. Rishi Patel, Dr. Nitin Gadkari

Dr. Virendra Pratap Singh, Dr. Arundhati Diwan, Dr. Supriya Barsode, Dr. Rishi Patel, Dr. Nitin Gadkari

Keywords: Corona, Covid-19, Lymphopenia in Covid-19, ARDS

Abstract

Aims: The novel corona virus originated in China and spread across all of Europe, United states of America before it held India in its grips. Patients presented with symptoms like fever, cough, myalgia and shortness of breath. The aim of this study was to describe the clinical profiles of Covid 19 positive cases admitted in Bharati Hospital and Medical college, Pune, a tertiary medical college hospital in Western India.

Material & Methods: A cross sectional observational study was done of 200 Covid19 positive patients. Detailed case history was taken of all the patients and investigations like laboratory tests, Chest Xray, CT scans were done and Real time reverse transcription polymerase chain reaction (RT-PCR) assay of 2019-nCoVRNA was done to confirm the diagnosis. The treatment and outcomes were recorded. All analysis were carried out using Metachart software.

Results: 200 Covid-19 positive patients admitted in Bharati Hospital and Medical college Pune were studied. Male patients constituted 70% of total patients and 95 patients were in the age group 18 to 39 years. 18.5% patients were asymptomatic. In those symptomatic, cough was the most common symptom (25.5%), dyspnoea in 15% with 14.5% having fever. Eighty-two patients (41%) had comorbidities in the form of hypertension, diabetes mellitus, chronic kidney disease, coronary artery disease or bronchial asthma. All 200 patients had raised inflammatory markers. Forty-five patients had SpO2 less than 94% out of which 12 patients went into ARDS during the course of treatment and needed intensive care.105 patients (52.5%) patients had lymphopenia and thrombocytopenia was seen in 10% cases. 45 cases required oxygen support. There was a total of 9
complications and four patients succumbed to the illness during the course of our study.

Conclusion: Older patients with associated comorbid conditions had greater risk for lung injury thus requiring oxygen support and these patients also had more derangement in their laboratory markers. Lymphopenia was the predominant finding in Covid 19 patients in this study. Chest X-ray proved sufficient for diagnosis, reducing the requirement of CT scans.

Conflict of Interest: None declared

Source of Support: None declared

References

1. Harapan H, Itoh N, Yufika A, Winardi W, Keam S, Te H, Megawati D, Hayati Z, Wagner AL, Mudatsir M. Coronavirus disease 2019 (COVID-19): A literature review. J Infect Public Health. 2020 May;13(5):667-673.
2. Ratti RM,Choudhary KD,VermaA,Acharya R,SoniG et al. COVID-19 clinical profile: A review based on current evidence. International Journal of Medical and Health Research.2020;6(5):04-06.
3. Bhandari S, Bhargava A, Sharma S, KeshwaniP,Sharma R, Banerjee S, et al. Clinical Profile of Covid19 Infected Patients Admitted in a Tertiary Care Hospital in North India. JAPI. 2020 May;68(5):13-17.