Relative Bioavailability of Liposomal Vitamin C – ‘VitaLip-C’
Abstract
Background: Vitamin C is a water-soluble vitamin and one of the most commonly used vitamins. With increasing vitamin
C intake, the plasma steady state concentration reaches a maximal level of about 70–80 μM. However, from the available
literature, it appears that a daily intake of about 200–400 mg of vitamin C ensures saturation of the blood in healthy individuals.
Bioavailability can be increased by various methods, such as encapsulation, micronisation, etc. VitaLip-C is a liposomal
form of vitamin C, which is shown to be clinically proven and evaluated by Transmission Electron Microscopy (TEM) for the
presence of liposomes.
Materials and Methods: In the present study, authors have studied the relative bioavailability of VitaLip-C with the marketed
formulation of vitamin C in animals.
Results and Conclusion: It has been observed that VitaLip-C has 88.76% higher relative oral bioavailability in comparison
to marketed formulation claiming 500 mg of vitamin C.
Conflict of Interest: Dr. Yogesh Dound is Propreitor, & Shivani Agawane and Khushbu Gupta are Research Associates
from Shreepad Shree Vallabh SSV Phytopharmaceuticals.
Source of Support: This study was sponsored by Shreepad Shree Vallabh SSV Phytopharmaceuticals
References
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