Reflections on the Current Scenario of Breast Cancer and Paradigm Shift in its Management: An Indian Context

Abstract

Breast cancer stands as a widespread malignancy impacting women on a global scale. Low-resource countries, including India, face a significant and increasing burden of breast cancer cases. Notably, a higher proportion of breast cancer diagnoses in India are now occurring among younger age groups. This trend is compounded by issues such as delayed diagnosis, presentation at advanced disease stages, and postponed initiation of treatment, all contributing to lower survival rates compared to Western nations. Late-stage diagnosis not only results in poorer treatment outcomes but also escalates the costs of treatment. Decisions regarding breast cancer treatment in India are influenced not just by medical factors but also by logistical and accessibility challenges. In the last decade, there have been remarkable advancements in breast cancer diagnosis and treatment, with the introduction of novel prognostic & diagnostic modalities as well as innovative treatment protocols and therapeutic options. These developments have led to substantial improvements in early disease detection, significantly enhancing overall survival rates, progression-free survival, and freedom from relapse. This progress marks a positive stride forward in the battle against breast cancer.