Renal Carcinoid Tumour

  • Dr. Tushar Aggarwal, Malhotra A, Mardi K, Puri S, Malhotra K, Goyal S
Keywords: Carcinoid, kidney, neuro-endocrine tumor, synaptophysin

Abstract

Carcinoid tumours are low grade malignant neuroendocrine tumours found mainly in small intestine, lungs.1 However primary carcinoid tumour is not normally present in the kidneys, this being an extremely rare renal malignant neoplasm with less than 100 cases reported so far,2,3 with majority of cases being associated with horse shoe kidneys. We describe a 39 years old male who presented with complaint of pain abdomen in left lumbar region, with solid renal mass detected on Computed Tomography. We treated the patient with radical nephrectomy. Pathological examination revealed tumor cells arranged in trabeculae, anastomosing cords, nests with peripheral palisading, and in cribriform pattern. The ‘tumor cells showed round to oval nuclei, stippled nuclear chromatin, inconspicuous nucleoli, indistinct cell borders and scant cytoplasm, findings consistent with a carcinoid tumor. IHC was positive for synaptophysin, chromogranin, and Panck. The patient has been kept on follow up to look for any local recurrence or systemic metastasis.

References

1. R. Murali, K. Kneale, N. Lalak, and W. Delprado. Carcinoid tumours of the urinary tract and prostate. Archives of Pathology and Laboratory Medicine. 2006; 11: 1693-1706.
2. A. O. Omiyale, A. K. G. Venyo. Primary carcinoid tumor of the kidney: a review of the literature. Advances in urology. 2013: 11.
3. T. Toshikazu, Y. Hayato, I. Atsushi et al. A case of Primary Renal Carcinoid Tumor. Case reports in Urology. 2015: 4 pages.
4. B. Krishnan, L. D. Truong, et al. Horseshoe kidney is associated with an increased relative risk of primary renal carcinoid tumor. Journal of Urology. 1997; 157: 2059-2066.
5. L. Guy, L. R. Begin, L. L. Oligny, G. B. Brock, S. Chevalier, et al. Searching for an intrinsic neuroendocrine cell in the kidney: an immunohistochemical study of the fetal, infantile, and adult
kidney. Pathology Research and practice. 1999; 195: 25-30.
6. F. R. Romero, S. Rais-Bahrami, S. W. Fine. Primary carcinoid tumors of the kidney. The Journal of Urology. 2006; 176: 2359- 2366.
7. D. E. Hansel, J. I. Epstein, E. Berbescu et al. Renal Carcinoid tumor: a clinicopathologic study of 21 cases. American Journal of Surgical Pathology. 2007; 31: 1539- 1544.
Published
2019-07-23
How to Cite
Dr. Tushar Aggarwal, Malhotra A, Mardi K, Puri S, Malhotra K, Goyal S. (2019). Renal Carcinoid Tumour. The Indian Practitioner, 69(10), 32-34. Retrieved from https://articles.theindianpractitioner.com/index.php/tip/article/view/369