Undifferentiated Embryonal Sarcoma of the Liver in an adult patient: Case report with review of literature
Keywords:
embryonal sarcoma, Computed tomography, liver, immunohistochemistry
Abstract
We present a case of undifferentiated embryonal sarcoma of liver (UESL), a rare and aggressive tumour with poor prognosis. It is an uncommon hepatic tumour, of mesenchymal origin, usually observed in children, and cases in adults are rare. We present a case in a 22 year old healthy male with only mild abdominal pain. On admission the patient had normal aspartate aminotransferase, alanine aminotransferase. He also tested negative for hepatitis and tumour markers. On Computed tomography (CT) scan a large solid cystic mass was seen which was diagnosed as UESL on immunohistochemistry.
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2. Stocker JT, Ishak KG. Undifferentiated (embryonal) sarcoma of the liver: Report of 31 cases. Cancer. 1978;42: 336-348.
3. Donovan EJ, Santulli TV. Resection of the left lobe of the liver for mesenchymoma: report of a case. Ann Surg. 1946;124:90-3.
4. Stout AP. Mesenchymoma, mixed tumor of mesenchymal derivates. Ann Surg. 1948;127:278- 90.
5. Chao-Liu Dai, Feng Xu, Hong Shu et al. Undifferentiated (embryonal) sarcoma of liver in adult: A case report World J Gastroenterol. 2005;11(6):926-929
6. Nishio J, Iwasaki H, Sakashita N et al. Undifferentiated (embryonal) sarcoma of the liver in middle-aged adults: smooth muscle differentiation determined by immunohistochemistry
and electron microscopy. Hum Pathol. 2003; 34: 246-252
7. Ma L, Liu YP, Geng CZ et al. Undifferentiated embryonal sarcoma of liver in an old female: case report and review of the literature. World Gastroenterol. 2008;14:7267-7270.
8. Aoyama C, Hachitanda Y, Sato JK et al. Undifferentiated (embryonal) sarcoma of the liver. A tumor of uncertain histogenesis showing divergent differentiation. Am J Surg Pathol. 1991;15:615-624.
9. Keating S, Taylor GP. Undifferentiated (embryonal) sarcoma of the liver: ultrastructural and immunohistochemical similarities with malignant fibrous histiocytoma. Hum Pathol. 1985; 16:693-699.
10. Cozzutto C, De Bernardi B, Comelli A et al. Malignant mesenchymoma of the liver in children: a clinicopathologic and ultrastructural study. Hum Pathol. 1981;12:481-485.
11. Nonomura A, Mizukami Y, Kadoya M et al. Angiomyolipoma of the liver: Its clinical and pathological diversity. J Gastroenterol. 1994;29:95-105.
12. Tsui WM, Yuen AK, Ma KF et al Hepatic angiomyolipomas with a deceptive trabecular pattern and HMB-45 reactivity. Histopathology. 1992;21:569- 573.
13. Pachera S, Nishio H, Takahashi Y et al. Undifferentiated embryonal sarcoma of the liver: case report and literature survey. J Hepatobiliary Pancreat Surg. 2008;15:536-544.
14. Grazi GL, Gallucci A, Masetti M et al. Surgical therapy for undifferentiated (embryonal) sarcomas of the liver in adults. Am Surg. 1996; 62: 901-906.
15. Lack EE, Schloo BL, Azumi N et al. Undifferentiated (embryonal) sarcoma of the liver. Clinical and pathologic study of 16 cases with emphasis on immunohistochemical features. Am J Surg Pathol. 1991;15:1-16
Published
2019-07-26
How to Cite
Dr. Nitin Jain, Magu S, Yadav R, Rohilla S, Jain S. (2019). Undifferentiated Embryonal Sarcoma of the Liver in an adult patient: Case report with review of literature. The Indian Practitioner, 69(6), 35-38. Retrieved from https://articles.theindianpractitioner.com/index.php/tip/article/view/432
Section
Case Reports
