Rosai Dorfman Disease
Abstract
Rosai Dorfman disease or Sinus histiocytosis with massive lymphadenopathy (SHML) is a benign, self-limiting disorder that commonly presents as massive bilateral
and painless cervical lymphadenopathy. We present a case of a 6 year old male child who presented with cervical lymphadenopathy with no other complaints and was diagnosed on fine needle aspiration cytology as a case of Rosai Dorfman disease. Patient was given low dose steroids and he responded well to become asymptomatic by 15 days.
References
1. Rosai J, Dorfman RF. Sinus histiocytosis with massive lymphadenopathy. Arch Pathol.1969; 87: 63- 70 .
2. Innocenzi D, Silipo V, Giombini S, Ruco L, Bosman C, Calviero S. Sinus histiocytes with massive lymphadenopathy- Rosai-Dorfman syndrome: case report with nodal and diffuse mucocutaneous involvement. J CutanPathol. 1998;25:563-7.
3. Bhaskar V, Swamy K, Reddy BK, Supe SS, Kumar RV. Sinus histiocytosis with nodal and extranodal involvement. A case report. J Indian Med Assoc. 2003;101:28-30.
4. Wright DH, Richards DB. Sinus histiocytosis with massive lymphadenopathy Rosai-Dorfman syndrome: Report of a case with widespread nodal and extranodal dissemination. Histopathology.
1981;5:697-709.
5. Abdollahi A, Ardalan F, Ayati M. Extranodal Rosai- Dorfman Disease of the kidney. Annals Saudi Med.2009; 29: 55-57.
6. Mard K, Charfi L, Dhouib R, et al. Extranodal Rosai- Dorfman disease: a case report with thyroid involvement. Annals de Pathol.2004; 24: 446-449.
7. Levine PH, Jahan N, Murari P, et al. Detection of Human Herpesvirus 6 in Tissues Involved by Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease). J Infect Dis.1992; 166: 291- 295.
8. Tsang WY, Yip TT, and Chan JK. The Rosai-Dorfman disease histiocytes are not infected by Epstein-Barr virus. Histopathology.1994; 25: 88-90.
9. Ambati S, Chamyan G, Restrepo R, et al. Rosai- Dorfman disease following bone marrow transplantation for pre-B cell acute lymphoblastic leukemia. Pediatr Blood Cancer.2008; 51: 433-435.
10. Lu D, Estalilla OC, Manning JT, et al. Sinus Histiocytosis with Massive Lymphadenopathy and Malignant Lymphoma Involving the Same Lymph Node: A Report of Four Cases and Review of the
Literature. Modern Pathology.2000;13:414-419.
11. Oka M, Kamo T, Goto N, et al. Successful treatment of Rosai-Dorfman disease with low-dose oral corticosteroid. J Dermatol. 2009; 36: 237-240.
12. Horneff G, Jurgens H, Hort W, et al. Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): response to methotrexate and mercaptopurine. Med PediatrOncol.1996; 27: 187-192.
13. Viraben R, Dupre A, and Gourget B. Pure cutaneous histiocytosis resembling sinus histiocytosis. ClinExpDermatol.1998; 13: 197-199.
2. Innocenzi D, Silipo V, Giombini S, Ruco L, Bosman C, Calviero S. Sinus histiocytes with massive lymphadenopathy- Rosai-Dorfman syndrome: case report with nodal and diffuse mucocutaneous involvement. J CutanPathol. 1998;25:563-7.
3. Bhaskar V, Swamy K, Reddy BK, Supe SS, Kumar RV. Sinus histiocytosis with nodal and extranodal involvement. A case report. J Indian Med Assoc. 2003;101:28-30.
4. Wright DH, Richards DB. Sinus histiocytosis with massive lymphadenopathy Rosai-Dorfman syndrome: Report of a case with widespread nodal and extranodal dissemination. Histopathology.
1981;5:697-709.
5. Abdollahi A, Ardalan F, Ayati M. Extranodal Rosai- Dorfman Disease of the kidney. Annals Saudi Med.2009; 29: 55-57.
6. Mard K, Charfi L, Dhouib R, et al. Extranodal Rosai- Dorfman disease: a case report with thyroid involvement. Annals de Pathol.2004; 24: 446-449.
7. Levine PH, Jahan N, Murari P, et al. Detection of Human Herpesvirus 6 in Tissues Involved by Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease). J Infect Dis.1992; 166: 291- 295.
8. Tsang WY, Yip TT, and Chan JK. The Rosai-Dorfman disease histiocytes are not infected by Epstein-Barr virus. Histopathology.1994; 25: 88-90.
9. Ambati S, Chamyan G, Restrepo R, et al. Rosai- Dorfman disease following bone marrow transplantation for pre-B cell acute lymphoblastic leukemia. Pediatr Blood Cancer.2008; 51: 433-435.
10. Lu D, Estalilla OC, Manning JT, et al. Sinus Histiocytosis with Massive Lymphadenopathy and Malignant Lymphoma Involving the Same Lymph Node: A Report of Four Cases and Review of the
Literature. Modern Pathology.2000;13:414-419.
11. Oka M, Kamo T, Goto N, et al. Successful treatment of Rosai-Dorfman disease with low-dose oral corticosteroid. J Dermatol. 2009; 36: 237-240.
12. Horneff G, Jurgens H, Hort W, et al. Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): response to methotrexate and mercaptopurine. Med PediatrOncol.1996; 27: 187-192.
13. Viraben R, Dupre A, and Gourget B. Pure cutaneous histiocytosis resembling sinus histiocytosis. ClinExpDermatol.1998; 13: 197-199.
Published
2019-08-10
How to Cite
Manish Tiwari, Chaudhary V, Khamkar A, Suryawanshi A. (2019). Rosai Dorfman Disease. The Indian Practitioner, 68(8), 51-53. Retrieved from https://articles.theindianpractitioner.com/index.php/tip/article/view/578
Section
Case Reports
